Rejuran Treatment in Korea: Everything You Need to Know About Salmon DNA Injections

 

 

Rejuran treatments have taken the Korean skincare world by storm, but many international patients still have questions about this revolutionary procedure. In this comprehensive guide, AB Plastic Surgery Korea's experts answer everything you've been wondering about Rejuran treatments.

 

 

 

1. What Is Rejuran and Why Is It So Popular in Korea?

Rejuran is an innovative skin treatment that originated in South Korea and has gained global recognition for its remarkable skin regeneration and anti-aging properties. Unlike traditional fillers or botox, Rejuran works differently:

• It contains polynucleotides (PN) extracted from salmon DNA

• These polynucleotides stimulate your skin's natural healing processes

• The treatment rebuilds and regenerates damaged skin cells

• Results in improved skin texture, elasticity, and overall quality

Rejuran has become a cornerstone treatment in Korea's advanced skincare landscape because it addresses fundamental skin health rather than simply masking signs of aging.

 

 

 

2. Is Rejuran a Filler? Understanding the Important Differences

One of the most common misconceptions is that Rejuran is a type of dermal filler. This is not accurate.

 

 

How Rejuran differs from fillers:

Aspect	Rejuran	Traditional Fillers
Primary Function	Skin regeneration and healing	Volume replacement and wrinkle filling
Main Ingredient	Polynucleotides (PN) from salmon DNA	Hyaluronic acid or other volumizing substances
How It Works	Stimulates collagen production and cell renewal	Physically fills space under the skin
Results Timeline	Gradual improvement over 4-8 weeks	Immediate volumizing effect
Longevity	6-12 months with improved skin quality	6-18 months with volume gradually decreasing
Best For	Overall skin quality, fine lines, acne scars	Deep wrinkles, volume loss, facial contouring

Think of Rejuran as a skin quality enhancer rather than a filler—it improves your skin from within rather than adding volume.

 

 

 

 

3. Different Types of Rejuran Treatments Available in Korea

At AB Plastic Surgery Korea, we offer several specialized Rejuran formulations, each designed for specific concerns:

 

 

Rejuran Healer

• The original and most popular formulation

• Ideal for overall skin regeneration

• Best for treating fine lines, enlarged pores, and improving elasticity

• Commonly used on face, neck, and décolletage

 

 

Rejuran I

• Higher concentration of polynucleotides

• Specifically formulated for deeper wrinkles

• Enhanced regenerative properties

• Suitable for more mature skin

 

 

Rejuran S

• Specialized for scar treatment

• Helps improve acne scarring and surgical scars

• Contains additional healing components

• May be used in conjunction with other scar treatments

 

 

Rejuran Eyes

• Specifically formulated for the delicate eye area

• Addresses dark circles, fine lines, and crepey skin

• Lower concentration to suit thin under-eye skin

• Minimal swelling compared to other treatments

 

 

4. The Science Behind Rejuran: How It Transforms Your Skin

Rejuran's effectiveness is backed by significant scientific research. Here's how this innovative treatment works at a cellular level:

• DNA Regeneration: The polynucleotides in Rejuran are similar to human DNA, allowing them to integrate with your skin cells.

• Cell Proliferation: Rejuran stimulates fibroblast cells, which produce collagen and elastin—the building blocks of youthful skin.

• Improved Blood Flow: Enhanced microcirculation brings more nutrients and oxygen to skin cells.

• Strengthened Skin Barrier: Repairs and reinforces your skin's protective barrier function.

• Anti-inflammatory Effects: Reduces inflammation, a key factor in skin aging and damage.

• Increased Hydration: Improves your skin's ability to retain moisture naturally.

This multi-faceted approach is why Rejuran delivers such comprehensive skin improvements rather than just addressing a single concern.

 

 

 

5. Is Rejuran Painful? What to Expect During Treatment

Many prospective patients wonder about the comfort level during Rejuran treatments. Here's what to expect at AB Plastic Surgery Korea:

 

 

Before Treatment

• Topical numbing cream is applied 30-45 minutes prior to treatment

• Your skin is thoroughly cleansed and prepped

• Photos are taken for before/after comparison

 

 

During Treatment

• Most patients describe the sensation as mild pinpricks

• Our advanced techniques minimize discomfort:

• Ultra-fine needles reduce pain

• Expert injection techniques avoid sensitive areas

• Temperature-controlled product for comfortable delivery

• The entire facial treatment takes approximately 15-30 minutes

 

 

Pain Management Options

• Standard topical anesthesia (included in all treatments)

• Premium nerve block options for extremely sensitive patients

• Cooling devices during treatment to reduce discomfort

• Pro-comfort injection techniques unique to our clinic

 

 

 

 

6. Rejuran Side Effects: What's Normal and What's Not

Understanding potential side effects helps you prepare for your Rejuran treatment:

 

 

Common and Normal Effects (2-3 days)

• Small injection bumps (mosquito bite-like appearance)

• Mild redness at injection sites

• Slight swelling, particularly in thinner-skinned areas

• Temporary sensitivity to touch

 

 

Less Common Effects (1-5% of patients)

Bruising at injection sites
Prolonged redness (3+ days)
Itching sensation during healing phase

 

 

Rare Complications (<1% of patients)

• Infection (prevented by strict sterile techniques)
• Allergic reactions
• Prolonged swelling or nodules

At AB Plastic Surgery Korea, our complication rate is significantly lower than the industry average due to our experienced practitioners, premium-quality products, and strict sterilization protocols.

 

 

 

7. How Many Rejuran Sessions Do You Need for Optimal Results?

Rejuran is not a one-and-done treatment. For optimal results, we recommend:

 

 

Initial Treatment Phase

• Standard protocol: 3 sessions spaced 4 weeks apart

• This establishes a foundation for skin regeneration

• Visible improvements typically begin after the second session

• By the third session, most patients see significant improvement in texture and elasticity

 

 

Maintenance Phase

• After completing the initial series, maintenance treatments every 6-12 months

• Younger patients (20s-30s) typically need less frequent maintenance

• Mature skin (40s+) benefits from treatments every 6 months

• Your provider will create a customized schedule based on your skin's response

 

 

Specialized Concerns

• Acne scarring may require 4-6 initial sessions for optimal improvement

• Deep wrinkles may benefit from combining Rejuran with complementary treatments

• Sun-damaged skin often requires the full series before dramatic improvements

 

 

 

 

8. Rejuran Recovery: What to Expect After Treatment

One of the advantages of Rejuran is its minimal downtime, but understanding the recovery process helps set realistic expectations:

 

 

Hours 0-12

• Small bumps at injection sites (resembling mosquito bites)

• Mild redness common, especially in sensitive areas

• Apply cool compress if needed for comfort

• Avoid touching or applying pressure to treated areas

 

 

Day 1-2

• Bumps begin to subside

• Redness significantly diminishes

• Makeup can be applied (mineral-based recommended)

• Most patients return to normal activities

 

 

Day 3-5

•  Typically all visible signs of treatment resolved

• Initial improvements in skin texture may be noticeable

• Normal skincare routine can be resumed

• Sun protection remains essential

 

 

Special Recovery Instructions

• Avoid direct sun exposure for 48 hours

• No saunas, hot baths, or intense exercise for 24 hours

• Refrain from alcohol consumption for 24 hours (reduces risk of bruising)

• Hold off on exfoliants or retinoids for 3 days

 

 

 

9. The Results: What Improvements Can You Expect from Rejuran?

Understanding realistic outcomes helps you determine if Rejuran is right for your concerns:

 

Immediate Results (1-2 weeks)

• Improved skin hydration

• Subtle glow and luminosity

• Initial improvement in fine lines

 

 

Medium-Term Results (1-3 months)

• Noticeable improvement in skin texture

• Reduced pore size

• Diminished fine lines

• Enhanced skin elasticity

• Improved overall tone

 

 

Long-Term Results (3+ months)

• Significant improvement in skin quality

• Reduction in acne scarring (when applicable)

• Enhanced skin resilience

• Natural, healthy appearance

• Long-lasting skin regeneration effects

 

 

What Rejuran Won't Do

• Provide immediate volume like fillers

• Replace the lifting effects of threads or surgery

• Completely eliminate deep wrinkles in a single session

• Change facial structure or features

Rejuran works best for patients seeking genuine skin quality improvements rather than dramatic structural changes.

 

 

 

 

10. Ideal Candidates: Is Rejuran Right for You?

Rejuran can benefit many skin types and concerns, but it's particularly effective for:

 

 

By Age Group

• 20s-30s: Preventative care, early fine lines, acne scarring, improving skin quality

• 30s-40s: Fine to moderate lines, enlarged pores, early loss of elasticity, dullness

• 50s+: Skin thinning, crepiness, moderate wrinkles, overall skin rejuvenation

 

 

By Skin Concern

• Texture issues: Uneven texture, roughness, lack of smoothness

• Aging signs: Fine lines, reduced elasticity, thinning skin

• Acne aftermath: Post-acne marks, shallow scarring, redness

• Environmental damage: Sun damage, pollution effects, stressed skin

 

 

Not Ideal For

• Patients seeking immediate dramatic results

• Those with severe deep wrinkles as sole concern (may need combination therapy)

• Individuals with fish allergies

• Active skin infections or inflammatory conditions

 

 

 

Take the Next Step with AB Plastic Surgery Korea's Premium Rejuran Experience

At AB Plastic Surgery Korea, we offer a comprehensive Rejuran experience tailored to your specific needs. Our approach includes customized formulation selection, advanced injection techniques, complementary treatment options, and dedicated international patient support. Begin your journey with a personalized consultation where our experts will assess your concerns, create a custom treatment plan, and schedule your sessions with flexibility for international visitors. As a leading aesthetic clinic in Korea, we provide exceptional care through our board-certified specialists, dedicated patient coordinators with translation services, state-of-the-art facilities in Gangnam, and comprehensive aftercare support. Experience the difference our specialized expertise makes in achieving healthier, more youthful skin through revolutionary Rejuran treatments.

 

 

 

 

Frequently Asked Questions About Rejuran

Is Rejuran FDA approved?

Rejuran is approved for use in many Asian countries, including South Korea, Japan, and Singapore. It is not currently FDA-approved in the United States, though similar DNA-based treatments are being developed for the US market.

 

 

Is Rejuran safe for all skin types?

Yes, Rejuran is generally safe for all Fitzpatrick skin types I-VI. It poses minimal risk of pigmentation issues compared to some laser treatments, making it suitable for darker skin tones.

 

 

Can Rejuran be used during pregnancy or breastfeeding?

As with most aesthetic treatments, we do not recommend Rejuran during pregnancy or breastfeeding due to the lack of specific safety studies in these populations.

 

 

How soon before a special event should I get Rejuran?

For special events, we recommend having your first Rejuran treatment at least 2-3 weeks prior. This allows any initial bumps to completely resolve and gives time for the first round of skin improvements to become visible.

 

 

Will my face look swollen after treatment?

Unlike fillers that can cause noticeable swelling, Rejuran typically causes only minimal and temporary swelling. The small injection bumps usually subside within 24-48 hours.